2
Why does the liver enlarge in thalassemia?
- 1 people answered
3 Votes
1 Contributor
3653 Views 
0 Saved
3 Votes 1 Contributor3653 Views 0 SavedYou might also be interested in
The main plasma lipid transport forms are triglyceride, free fatty acid and cholesteryl ester. Triglycerides are used in the making of some hormones and enzymes the body needs. It is also used in the manufacture of cell membranes in our bodies. Even if we limited our consumption of them, the liver w....
Hello, please describe your problem in detail, then only we'll be able to suggest the right doctor, hospital and provide you treatment costs. You can call us on +91-8010994994 and talk to our medical expert.
The liver itself has no sensory nerve endings in its interior. It does have sensory nerve endings in its surface.The organ itself can’t feel pain. Even so, the sensation of liver pain can occur because the layer of tissue that surrounds the organ called Glisson’s Capsule does contain nerves.This is ....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.