2
Why does the liver enlarge in thalassemia?
- 1 people answered
3 Votes
1 Contributor
2041 Views 
0 Saved
3 Votes 1 Contributor2041 Views 0 SavedYou might also be interested in
The liver itself has no sensory nerve endings in its interior. It does have sensory nerve endings in its surface.The organ itself can’t feel pain. Even so, the sensation of liver pain can occur because the layer of tissue that surrounds the organ called Glisson’s Capsule does contain nerves.This is ....
Tramadol is harmful when taken in large doses but it can be harmful even in normal doses if you have an unhealthy liver. Tramadol is a medication used for the therapy of mild-to-moderate pain. Tramadol overdose can result in acute liver failure. If you have liver diseases or a history of liver disea....
Our liver has a tremendous regenerating capacity. So in order for the virus to be successful, it has to elude this destructive power of inflammation and immunity. When the body is attacked by hepatitis virus, liver cells get damage but in the end, the virus is ousted, repairs commence and things are....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.