0
Breast Cancer: Is the ER (estrogen receptor) something genetic or is it variable based on medication (ie. chemotherapy)?
- 1 people answered
1 Vote
1 Contributor
1869 Views 
0 Saved
1 Vote 1 Contributor1869 Views 0 SavedYou might also be interested in
It might depend on the cancer. Stage I breast cancer is the earliest stage of invasive breast cancer. At this stage, the cancer cells have spread beyond the original location and into the surrounding breast tissue. Because a stage I tumor is small, it may be difficult to detect. However, breast s....
Hello, please describe your problem in detail, then only we'll be able to provide you treatment costs. You can call us on +91-8010994994 and talk to our medical expert.
HER2 is a gene that creates HER2 proteins or receptors. These receptors help control growth and repair of breast cells. An overexpression of HER2 protein causes out-of-control reproduction of breast cells. HER2-positive breast cancers are known to be more aggressive than HER2-negative breast canc....
Mahima Chaudhary
Receptors are proteins in or on cells that can attach to certain substances in the blood. Normal breast cells and some breast cancer cells have receptors that attach to the hormones estrogen and progesterone, and depend on these hormones to grow.
The breast tissue estrogen receptor is both genetic and variable in the presence of chemotherapy and other medications.
Breast cancer cells may have one, both, or none of these receptors.
ER-positive: Breast cancers that have estrogen receptors are called ER-positive (or ER+) cancers.
PR-positive: Breast cancers with progesterone receptors are called PR-positive (or PR+) cancers.
Keeping these receptors from attaching to the hormones can help keep the cancer from growing and spreading. There are drugs that can be used to do this.
Knowing the hormone receptor status of your cancer helps doctors decide how to treat it. If your cancer has one or both of these hormone receptors, hormone therapy drugs can be used to either lower estrogen levels or stop estrogen from acting on breast cancer cells. This kind of treatment is helpful for hormone receptor-positive breast cancers, but it doesn’t work on tumors that are hormone receptor-negative (both ER- and PR-negative).