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Why does the liver enlarge in thalassemia?
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Sir do ur hospital do treatment for liver jondis
Foods which can be easily digested by our digestion system and ac easily be detoxified by the liver are best for the liver. Food with high nutritional value is also good for the liver. Detoxification is the removal of toxins from our body. Sometimes vegetables are covered with pesticides and inorgan....
The liver is divided into two lobes by the middle hepatic vein: the right lobe of liver and the left lobe of the liver. The right lobe of the liver is larger than the left lobe of the liver. The right lobe liver has four sections divided by the portal vein. Each of these sections contains branche....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.