0
Breast Cancer: Is the ER (estrogen receptor) something genetic or is it variable based on medication (ie. chemotherapy)?
- 1 people answered
1 Vote
1 Contributor
1774 Views 
0 Saved
1 Vote 1 Contributor1774 Views 0 SavedYou might also be interested in
Generally, women having their routine mammogram will receive a letter within one month with normal results. But if the doctor finds something suspicious, they’ll call you back, mostly within just 5 days, to take fresh pictures or other tests. Yes, that call may seem to be scary, but a suspicious fin....
No, but. Cancer during pregnancy is not an uncommon thing but cancer itself rarely affects the growing baby directly. The cancers that tend to occur during pregnancy are also more common in younger people. These cancers include - Cervical Cancer, Breast Cancer, Thyroid Cancer, Melanoma, Gestat....
Genes and genetic variations in our body contribute to the bodily functions and overall health. This also includes the possibility of having various diseases which are hereditary or developed in our body due to changes in the genetic codes. BRCA -1 & BRCA – 2 are two genes which are linked to He....
Mahima Chaudhary
Receptors are proteins in or on cells that can attach to certain substances in the blood. Normal breast cells and some breast cancer cells have receptors that attach to the hormones estrogen and progesterone, and depend on these hormones to grow.
The breast tissue estrogen receptor is both genetic and variable in the presence of chemotherapy and other medications.
Breast cancer cells may have one, both, or none of these receptors.
ER-positive: Breast cancers that have estrogen receptors are called ER-positive (or ER+) cancers.
PR-positive: Breast cancers with progesterone receptors are called PR-positive (or PR+) cancers.
Keeping these receptors from attaching to the hormones can help keep the cancer from growing and spreading. There are drugs that can be used to do this.
Knowing the hormone receptor status of your cancer helps doctors decide how to treat it. If your cancer has one or both of these hormone receptors, hormone therapy drugs can be used to either lower estrogen levels or stop estrogen from acting on breast cancer cells. This kind of treatment is helpful for hormone receptor-positive breast cancers, but it doesn’t work on tumors that are hormone receptor-negative (both ER- and PR-negative).