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Why don't we always find cholestasis in cirrhosis?
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Liver pain could be felt at the upper portion of the abdomen, on the right-hand side. This could be a sign of a severe disease. Liver pain can arise for various reasons. It is important to find out what is causing the pain and to get treatment to prevent irreversible damage. It can take several for....
The enlargement of Liver happens due to continuous transfusions without adequate chelation. If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelatio....
Anamika Sharma
In cholestasis, the movement of bile a digestive fluid which is produced by the liver is impaired at somewhere between the liver cells which produce bile and the first segment of the small intestine called duodenum. When bile is stopped from flowing, the pigment bilirubin which is a waste product formed due to breaking down of old or damaged red blood cells escapes into the bloodstream and accumulates. This binds with bile in the liver, moves through the bile ducts into the digestive tract, and is eliminated from the body. But the disease cirrhosis is due to the complication of the liver which is due to loss of liver cells and scarring of the liver. When liver cells are lost it is not possible that bile will be impaired between cells which produce bile.