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Why does liver disease cause low platelets?
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When a sonographic examination of your liver is done, the texture of the liver is highlighted. A normal liver's texture is uniform/ smooth. When the surface of the liver is irregular/ not uniform i.e. the liver parenchyma is irregular, it indicates some form of liver disease. Incase your reports ind....
Portal vein carries things away from the intestines and stomach & headed it to the liver because of which the liver receives regular blood from the artery & the intestines, which is headed from the gut to the liver for processing. These sources of blood drain from the liver in the hepatic ve....
Mongolia has the world’s highest rate of liver cancer mortality—six times the global average—and the number are increasing. According to the World Health Organization estimation, one out of every 10 deaths in Mongolia is from hepatocellular carcinoma or cirrhosis (which is often observed as a precur....
Saurabh Rawat
Low platelets count is one of the major symptoms of liver disease.Reduction of platelets which is also known as Thrombocytopenia occurs mainly due to reduced thrombopoietin. Thrombopoietin is actually a glycoprotein hormone generated by the liver & kidney that regulates the creation of platelets.
Historically, thrombocytopenia was thought to arise from the increased pooling of platelets in the enlarged spleen due to portal hypertension. Portal hypertension may cause the spleen to enlarge and retain white blood cells and platelets, reducing the numbers of these cells and platelets in the blood, but spleen enlargement alone was not the only factor for reduction in platelets.Other factors such as Increased destruction of platelets within the spleen, intrasplenic production of autoantibodies, and plasma expansion resulting in hemodilution can also contribute to thrombocytopenia.