0
What is the maximum plasma level of tamoxifen that can be achieved in breast cancer patients?
- 1 people answered
0 Vote
1 Contributor
1269 Views 
0 Saved
0 Vote 1 Contributor1269 Views 0 SavedYou might also be interested in
Good news! The short answer is a resounding no. Cow milk’s relationship with breast cancer has been studied extensively over the past 25 years, and while the details of the studies don’t always agree, most of the studies agree on the basics: that dairy is not associated with an increased risk for br....
While you can’t change some breast cancer risk factors – family history and aging, for example – there are others that you can control. Here are 5 ways to help protect your breast health: Watch your weight as being overweight or obese increases breast cancer risk. This is especially true after....
Please mention if it is around the nipple area as well and with/without discharge. What kind of pain is it? Does it occur during your periods? Once I know answers to these, I would be able to guide you better.
Mithun Kumar
Tamoxifen is a highly effective endocrine treatment for breast cancer in the adjuvant and metastatic settings. Data from several large randomized clinical trials indicate that tamoxifen is also valuable in the prevention of breast cancer in women at high risk for the disease. However, not all women benefit from tamoxifen, and the side effect profiles vary considerably from patient to patient.
Tamoxifen treatment promotes significant changes both in the plasma concentration of an important marker associated with an increased risk of Cardio Vascular Disease (CVD) and in functional parameters of cardiac performance in women with breast cancer who have previously undergone chemotherapy. Previous studies had also confirmed the cardiotoxic effects of chemotherapy.
Chronic use of tamoxifen significantly reduces the plasma concentrations of CVD biomarkers (CRP, Apo B, and the Apo-B/Apo-A ratio) in women with breast cancer who underwent chemotherapy. Several study suggests the need for a careful cardiovascular evaluation and the medical monitoring of women with breast cancer to reduce the morbidity and mortality associated with cancer treatment complications.