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Breast Cancer: Is the ER (estrogen receptor) something genetic or is it variable based on medication (ie. chemotherapy)?
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Yes. In both cases, the reason is due to the activities of estrogen receptor (specifically Estrogen Receptor alpha), which is known to be a tumour promoter. Endometrial cancer is a type of uterine cancer that involves the lining of the uterus. It is seen in women who take estrogen-only and still ....
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One can start driving after 6 weeks post-surgery to be on the safer side. If other additional treatments are going on, it is best to ask your doctor for such instructions.
Mahima Chaudhary
Receptors are proteins in or on cells that can attach to certain substances in the blood. Normal breast cells and some breast cancer cells have receptors that attach to the hormones estrogen and progesterone, and depend on these hormones to grow.
The breast tissue estrogen receptor is both genetic and variable in the presence of chemotherapy and other medications.
Breast cancer cells may have one, both, or none of these receptors.
ER-positive: Breast cancers that have estrogen receptors are called ER-positive (or ER+) cancers.
PR-positive: Breast cancers with progesterone receptors are called PR-positive (or PR+) cancers.
Keeping these receptors from attaching to the hormones can help keep the cancer from growing and spreading. There are drugs that can be used to do this.
Knowing the hormone receptor status of your cancer helps doctors decide how to treat it. If your cancer has one or both of these hormone receptors, hormone therapy drugs can be used to either lower estrogen levels or stop estrogen from acting on breast cancer cells. This kind of treatment is helpful for hormone receptor-positive breast cancers, but it doesn’t work on tumors that are hormone receptor-negative (both ER- and PR-negative).