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Cancer Research: What is the sensitivity and specificity of the BRCA1 and 2 mutations?
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The risk is so low that it is impossible to read using tables of published health data and statistics. Children do get cancer, but very rarely breast cancer. Statistics will often group women aged 15–39 as “young women” but this is very misleading as the bump in cases begins in women over 20, or eve....
Cancer is by definition abnormal growth of tissue which spreads and causes damage. The actual mechanism why and how it happens is the subject of a great deal of study but appears to involve small groups of cancer cells invading and breaking off in blood and lymph vessels and being carried along to d....
Generally, women having their routine mammogram will receive a letter within one month with normal results. But if the doctor finds something suspicious, they’ll call you back, mostly within just 5 days, to take fresh pictures or other tests. Yes, that call may seem to be scary, but a suspicious fin....
Nidii Berwal
Genes and genetic variations in our body contribute to the bodily functions and overall health. This also includes the possibility of having various diseases which are hereditary or developed in our body due to changes in the genetic codes. BRCA -1 & BRCA – 2 are two genes which are linked to Hereditary Breast and Ovarian Cancer. These genes produce tumor suppressor proteins which help to repair damaged DNA. When either of these genes have mutations, it increases the risk of cancer. BRCA 1 & BRCA 2 testing should be considered if: You had breast cancer at early age Your mother, sister, or daughter had breast cancer at early age or ovarian cancer. You are a woman with 1st degree relative who’s diagnosed with bilateral breast cancer before age of 50 The men in your family have strong history of breast/ ovarian cancer. Women who have BRCA 1 gene mutation are at higher risk of triple negative breast cancer while BRCA 2 carriers have breast cancers that are Estrogen Receptor positive. BRCA 1/2 mutations increase the risk of ovarian cancer.