2
Why does the liver enlarge in thalassemia?
- 1 people answered
3 Votes
1 Contributor
2260 Views 
0 Saved
3 Votes 1 Contributor2260 Views 0 SavedYou might also be interested in
There are mainly two nootropics which are toxic to live:- 1. Pyritinol - It is a particle, which basically has two vitamin B6 molecules connected to each other. It is also known as pyrithioxine. A molecule with fundamentally two molecules bound together by two sulphur particles. Pyritinol is stimul....
The liver itself has no sensory nerve endings in its interior. It does have sensory nerve endings in its surface.The organ itself can’t feel pain. Even so, the sensation of liver pain can occur because the layer of tissue that surrounds the organ called Glisson’s Capsule does contain nerves.This is ....
Liver transplant being complex process is done at high risk. To reduce chances or risk from the patient side they are given anaesthesia which makes them unconscious. Generally, everyone is unconscious during the liver transplant. Only in rare cases, patients are kept conscious due to some other medi....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.