0
What is the maximum plasma level of tamoxifen that can be achieved in breast cancer patients?
- 1 people answered
0 Vote
1 Contributor
1339 Views 
0 Saved
0 Vote 1 Contributor1339 Views 0 SavedYou might also be interested in
Vulvar Paget's disease is a type of skin cancer of the Vulva. It presents as redness, velvety appearance with white islands of tissue. This is accompanied by itching and pain. If you have any such symptoms, contact your oncologist/gynaecologist for further treatment.
Mammograms are performed today for two reasons: they help detect breast cancer and also help confirm a diagnosis if another screening option shows the presence of cancerous cells. Mammograms might be able to help screen for breast cancer in some cases, but they do nothing to help prevent or treat br....
Please mention if it is around the nipple area as well and with/without discharge. What kind of pain is it? Does it occur during your periods? Once I know answers to these, I would be able to guide you better.
Mithun Kumar
Tamoxifen is a highly effective endocrine treatment for breast cancer in the adjuvant and metastatic settings. Data from several large randomized clinical trials indicate that tamoxifen is also valuable in the prevention of breast cancer in women at high risk for the disease. However, not all women benefit from tamoxifen, and the side effect profiles vary considerably from patient to patient.
Tamoxifen treatment promotes significant changes both in the plasma concentration of an important marker associated with an increased risk of Cardio Vascular Disease (CVD) and in functional parameters of cardiac performance in women with breast cancer who have previously undergone chemotherapy. Previous studies had also confirmed the cardiotoxic effects of chemotherapy.
Chronic use of tamoxifen significantly reduces the plasma concentrations of CVD biomarkers (CRP, Apo B, and the Apo-B/Apo-A ratio) in women with breast cancer who underwent chemotherapy. Several study suggests the need for a careful cardiovascular evaluation and the medical monitoring of women with breast cancer to reduce the morbidity and mortality associated with cancer treatment complications.