0
Cancer Research: What is the sensitivity and specificity of the BRCA1 and 2 mutations?
- 1 people answered
0 Vote
1 Contributor
1654 Views 
0 Saved
0 Vote 1 Contributor1654 Views 0 SavedYou might also be interested in
Some cancer treatments, like chemotherapy or radiation, can cause side effects like nausea or fatigue, but it’s not the same for everyone. If you’re feeling sick, talk to your doctor—they can prescribe medicines to help with nausea or suggest lifestyle tips to boost your energy. Eating small, freque....
There are several persistent internet rumours about potential causes of breast cancer. One is that wearing a bra, or wearing an underwire bra, causes the disease. The idea that bras may cause cancer was fuelled by the 1995 book called Dressed to Kill by Sydney Ross Singer and Soma Grismaijer. It cla....
Do you have a blue vein in your breast? If so, it may be nothing but a cosmetic problem. In most of the cases are harmless and tend to fade by themselves. Sometimes, however, blue veins in breasts can indicate the presence of an underlying medical condition. It is normal for you to worry if you not....
Nidii Berwal
Genes and genetic variations in our body contribute to the bodily functions and overall health. This also includes the possibility of having various diseases which are hereditary or developed in our body due to changes in the genetic codes. BRCA -1 & BRCA – 2 are two genes which are linked to Hereditary Breast and Ovarian Cancer. These genes produce tumor suppressor proteins which help to repair damaged DNA. When either of these genes have mutations, it increases the risk of cancer. BRCA 1 & BRCA 2 testing should be considered if: You had breast cancer at early age Your mother, sister, or daughter had breast cancer at early age or ovarian cancer. You are a woman with 1st degree relative who’s diagnosed with bilateral breast cancer before age of 50 The men in your family have strong history of breast/ ovarian cancer. Women who have BRCA 1 gene mutation are at higher risk of triple negative breast cancer while BRCA 2 carriers have breast cancers that are Estrogen Receptor positive. BRCA 1/2 mutations increase the risk of ovarian cancer.