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What is the ESR Level in Cancer Patients?

This article reviews the ESR test and ESR Level in cancer patients. You will also get to know normal as well as abnormal ESR levels in males and females. Moreover, you will get insights into the role of ESR in detecting cancer and what level of ESR indicates cancer. Besides this, you will learn how ESR contributes to cancer diagnosis.

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If your body has a high inflammation level, your doctor may recommend an ESR test. ESR is a particular kind of test that is abbreviated as an erythrocyte sedimentation rate. This specific test helps to identify or determine how quickly or rapidly red blood cells (RBCs) settle in the test tube, with a high rate of settlement indicating a high inflammation rate. ESR, a sedimentation or sed rate test, gives you information about your current health condition.

People often wonder if the ESR can detect cancer. To answer such a question, herein, we have given a detailed overview of the ESR test, which may help you understand what the ESR level indicates and the severity of the cancer by the ESR level. 

Glance At The Topic:

  • ESR test is a blood test used to detect the protein levels in the blood.

  • An ESR test showing high blood protein levels means the presence of inflammation in the body, indicating underlying chronic diseases such as cancer. 

  • ESR is a marker of inflammation that can give a hint to detect the cancer early or also help watch how well patients are responding to a cancer treatment.

  • The ESR normal range in females is 0 to 20 mm/hr and the ESR normal range in males is 0 to 15 mm/hr.

  • ESR range of 110 mm/hr and above indicates the chances of advanced cancer.

  • High levels of ESR are a strong indicator of undiagnosed cancer and are linked to poorer survival. 

What is the ESR Test?

ESR is a blood test known as a "Sed rate test” that evaluates certain protein levels in the blood that can show the presence of inflammation. Too much protein levels leads to inflammation which indicates the presence of certain diseases, including cancer. Typically, it calculates the rate of blood cells (specifically RBC, red blood cells, or erythrocytes) that settle at the bottom of the test tube. This settlement of the blood cells gives essential information regarding the body's inflammation.

The sedimentation rate (sed rate) is a non-specific blood test that measures inflammation in the body and is not a direct indicator of cancer, but elevated sed rates can sometimes be associated with various medical conditions, including cancer.

You may also read about: How to reduce ESR levels in Blood

What is the ESR Level in Cancer Patients?

The ESR test is measured in mm/hr (millimeters per hour)- the higher the level of mm/hr, the higher the presence of inflammation, the higher the chance of cancer. When the cancer ESR level of an individual is above 100 mm/hr, it indicates the risks of advanced cancer. A study states that, in the case of females, there is generally a high level of ESR compared to males that increases with age. The levels of ESR may differ based on some factors such as type and stage of cancer. For instance, in a few cancer cases, the ESR normal range in females might be within 20 mm/hr and the ESR normal range in males is 15 mm/hr. However, this normal range may increase in other cases that can predict a health condition like cancer.

Other factors that might affect ESR levels may include the shape and size of RBCs, the presence of inflammation, protein levels in the blood, etc. The following table lists the normal and abnormal ESR levels in men, women, and children:

Age (as per gender type)

Range of ESR (normal rate) mm/hr

Range of ESR (abnormal rate) mm/hr

Females under the age of 50

Between 0 to 20

Above or equivalent (the danger level) to 20

Males under the age of 50

In between 0 to 15

Above or equivalent (the danger level) to 15

Females over the age of 50

In between 0 to 30

Above the level of 30

Males over the age of 50

Between 0 and 20

Above the level of 20

Children below 18

Between 0 and 10

Above the level of 10

If your ESR test indicates a level of 100 mm/hr. This is the most dangerous level ever indicated. This is the most activated stage of disease, where you may be attacked with the bacteria of the following diseases-

  1. Cancer

  2. Diabetes

  3. Cardiovascular disease

If you have a particular inflammation or illness causing inflammation, your cancer doctor may recommend an ESR test along with other tests underlying the medical condition or its status. ESR values are typically descriptive as per the age of the person, sex of the person, or come with a higher or lower level of indication of illness. Certain medications can also cause an increase in the level of settlement of RBCs. Therefore, you may discuss the diet plan or medicines with your doctor in advance.

Also Read: How To Reduce Inflammation in The Body Fast

Can ESR Detect Cancer?

ESR alone can not detect cancer. However, ESR is a marker of inflammation. This means it gives a hint that can help professionals detect cancer early or watch how well a patient is responding to a specific treatment. The high levels of ESR can indicate increased inflammation and there is a connection between inflammation and cancer progression. Well, inflammation is the way the body fights against certain infections or injuries. When a person is living with cancer, their immune system finds it challenging to protect against the cancer cells, which as a result releases cells that lead to inflammation. So, the higher the ESR levels, the higher the inflammation in the body, and the more the chances of developing cancer. 

What Level of ESR Indicates Cancer?

When the ESR level of a person with solid cancerous tumors is above 100 mm/hr, it indicates the spreading of the cancer from its origin. The levels of ESR in cancer patients can differ based on certain factors such as type and stage of cancer. In some of the cases, the normal range of ESR in women may be within 20 mm/hr and in men 15 mm/hr. However, in other cases, this normal range may increase which can indicate the possibility of some issues in the body. Extremely high levels of ESR are linked with poor outcomes in some cancer types. As per research, increased ESR might be a precise indicator of cancer recurrence after treatment. 

Does High ESR Mean Cancer?

High levels of ESR are a strong indicator of undiagnosed cancer and are linked to poorer survival. Increased ESR provides an understanding of the presence of inflammation in the body of patients living with cancer. The higher the ESR levels, the higher the amount of inflammation. This may help the doctors adjust the cancer treatment accordingly. Additionally, the high ESR levels also can indicate cancer progression (spread or growth of cancer) which may adversely affect the chances of survival of cancer patients.

Is ESR 40 Dangerous?

Yes, the levels of ESR 40 in the body are dangerous and are considered indicators of the presence of certain diseases, including cancer. This level of ESR can result in inflammation and increased inflammation can increase the risks of advanced cancer. How? The immune system of the person living with cancer struggles a lot to fight off cancer cells and in turn, the body releases some inflammation-causing cells. When the inflammation increases in the body, it leads to the potential risk of developing cancer. 

What is the ESR Normal Range in Male and Female?

In general, the normal range of ESR in females is more than the males which increases with age. Moreover, the ESR levels might also vary based on the types and stages of cancer. Typically, the ESR normal range in females falls within 20 mm/hr and the ESR normal range in males is 15 mm/hr. However, this normal range may highly rise in some cases like a range above 100 mm/hr can indicate the risk of cancer development.

How ESR Is Helpful For Cancer Diagnosis?

ESR levels can be very useful in cancer diagnosis in certain ways such as:

  • Screening mode: ESR levels can act as a screening mode which can help detect possible health issues. For instance, high ESR levels may indicate the presence of cancer.

  • Inflammation indicator: Increased ESR levels can show the presence of inflammation which can be taken as a signal of cancer that instigates further analysis of the health.

  • Treatment response: ESR levels can be used to track the response of the cancer patients to the treatment. Any changes in levels of ESR may show the effectiveness of the treatment.

Summing Up

Now, you may know in detail, what is the ESR level in cancer patients. ESR levels are a crucial indicator of good health. An increase in ESR levels is commonly found in cancer patients. ESR test and some other specific tests can help the doctor diagnose cancer. In patients struggling with cancer, ESR levels can vary based on some factors such as cancer type and stage. In certain cases of cancer, the normal ESR range is within 15 mm/hr in men and 20 mm/hr in women while in other cases the range can rise, indicating a health issue. Although an ESR test helps you give information regarding the cancer, it also helps to provide other essential details like the presence of other diseases such as diabetes and cardiovascular disease, especially when there is no likelihood of inflammation.

Frequently Asked Questions

Can ESR be normal in cancer?

ESR in cancer patients varies according to the stages and treatment of the patient.

Does ESR increase in cancer?

In malignancies, ESR is usually elevated in the cancer patient. The cause may be the advanced disease and line of treatment.

What ESR level indicates cancer?

If ESR is higher than 100 mm/hr, this indicates active illnesses like diabetes, cancer, and cardiovascular disease.

Is ESR high in cancer?

Cancer and ESR levels are directly related to each other. It is mainly diagnosed with high ESR in the case of cancer. Additionally, other diseases like inflammation and tumors also lead to high ESR.

What are the normal ranges of ESR?

The ESR normal range in females is 0 to 20 mm/hr and ESR normal range in males is 0 to 15 mm/hr.

Can esr detect cancer?

ESR (erythrocyte sedimentation rate) is a non-specific test that can be elevated in the presence of inflammation, but it cannot directly detect cancer.

What is esr test?

An erythrocyte sedimentation rate (ESR) is a blood test that can show if you have inflammation in your body.

Why esr is high?

If an ESR test shows that your red blood cells sink faster than normal, it may mean you have a medical condition causing inflammation. The speed of your test results is a sign of how much inflammation you have. Faster ESR rates mean higher levels of inflammation.

Is esr 40 dangerous?

Yes! Patients with ESR 40 indicates presence of infection, chronic condition, heart failure, anaemia, or other condition that can result in inflammation.