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Why does the liver regenerate itself?
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Anamika Sharma
The liver is the only organ in the living being which has the capability to regenerate after injury and surgeries. In mammals only mass of liver is replaced but not shape therefore the process of regeneration is compensatory growth. But in lower size species both shape and size can be replaced. The liver regeneration is due to replication of liver cell which follows the removal of tissue (partial hepatectomy) and enlargement of hepatocytes followed by proliferation of hepatocyte. They are also capable of transdifferentiating into other cell types such those of the biliary system. The liver is the main site of drug detoxification. It is exposed to many chemicals in the body which may lead to cell death and injury. Thus the liver can regenerate damaged tissue rapidly preventing damage. This ability of the liver to regenerate is called homeostasis.