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Is breast cancer HER2-positive curable?
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Tamoxifen is a highly effective endocrine treatment for breast cancer in the adjuvant and metastatic settings. Data from several large randomized clinical trials indicate that tamoxifen is also valuable in the prevention of breast cancer in women at high risk for the disease. However, not all women ....
Because they are derived from normal cells that have hormone receptors and the normal cells must respond to hormones in order to fulfil their function. A high proportion of breast cancers are Estrogen Receptor Positive. This means they have a large number of estrogen receptors, indicating that estro....
Yes. In both cases, the reason is due to the activities of estrogen receptor (specifically Estrogen Receptor alpha), which is known to be a tumour promoter. Endometrial cancer is a type of uterine cancer that involves the lining of the uterus. It is seen in women who take estrogen-only and still ....
Kanishka Pandey
HER2 is a gene that creates HER2 proteins or receptors. These receptors help control growth and repair of breast cells. An overexpression of HER2 protein causes out-of-control reproduction of breast cells.
HER2-positive breast cancers are known to be more aggressive than HER2-negative breast cancers and are more likely to recur than HER2-negative breast cancer. The recurrence usually takes place within five years of treatment.
The good news is that recurrence is less likely these days than ever before. This is largely due to the latest targeted treatments. In fact, most people treated for early stage HER2-positive breast cancer don’t relapse. If your breast cancer is HR-positive, hormonal therapy may help reduce the risk of recurrence.
Your treatment plan will probably include a combination of therapies such as:
Targeted treatments (medicines like Herceptin, Kadcyla, Perjeta and Tykerb are used in this process) Once the treatment ends, you’ll still need periodic testing for signs of recurrence.