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Why does glucagon only target liver cells and what are some examples?
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Liver sinusoidal endothelial cells are constituted of a sinusoidal wall which is also called as endothelium or endothelial lining. The liver sinusoids are unique capillaries because of the presence of open pores or fenestrae lacking a diaphragm and a basal lamina underneath the endothelium, which di....
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Hormones which stimulate glycogenolysis in the liver are Glucagon, catecholamines, Adrenaline thyroxine and sometimes insulin deficiency also stimulate glycogenolysis. Adrenaline is produced due to the condition of stress which stimulates glycogenolysis in the liver of human beings. Glucagon is a ho....
Mahima Chaudhary
Liver cells or hepatocytes have glucagon receptors. Glucagon can easily target the liver. When glucagon binds to the glucagon receptors it is then converted into individual glucose molecules by liver cell and release them into the bloodstream. This process is known as glycogenolysis. Glucagon afterwards encourages the liver and kidney to synthesize additional glucose by the process gluconeogenesis.
Glucagon has examples like it stimulates the breakdown of glycogen stored in the liver and Glucagon activates hepatic gluconeogenesis. It also exerts control over two pivotal metabolic pathways within the liver.