2
Why does the liver enlarge in thalassemia?
- 1 people answered
3 Votes
1 Contributor
2092 Views 
0 Saved
3 Votes 1 Contributor2092 Views 0 SavedYou might also be interested in
An increase in the SGOT and SGPT levels is an indication of liver damage. The normal level of 30 for males and 19 for females if it reaches it medical attention is required. SGPT levels in the blood are thus compared with liver damage for example, from viral hepatitis or with compared to the heart f....
The liver itself has no sensory nerve endings in its interior. It does have sensory nerve endings in its surface.The organ itself can’t feel pain. Even so, the sensation of liver pain can occur because the layer of tissue that surrounds the organ called Glisson’s Capsule does contain nerves.This is ....
Liver pain could be felt at the upper portion of the abdomen, on the right-hand side. This could be a sign of a severe disease. Liver pain can arise for various reasons. It is important to find out what is causing the pain and to get treatment to prevent irreversible damage. It can take several for....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.