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Why does glucagon only target liver cells and what are some examples?
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Gluconeogenesis is a metabolic process that results in the generation of glucose from non-carbohydrate carbon substrates like lactate, glycerol, and glycogenic amino acids. Liver cells or hepatocytes have glucagon receptors. Gluconeogenesis occurs in the kidneys and only in the liver. This is due to....
Mahima Chaudhary
Liver cells or hepatocytes have glucagon receptors. Glucagon can easily target the liver. When glucagon binds to the glucagon receptors it is then converted into individual glucose molecules by liver cell and release them into the bloodstream. This process is known as glycogenolysis. Glucagon afterwards encourages the liver and kidney to synthesize additional glucose by the process gluconeogenesis.
Glucagon has examples like it stimulates the breakdown of glycogen stored in the liver and Glucagon activates hepatic gluconeogenesis. It also exerts control over two pivotal metabolic pathways within the liver.